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Anti-Androgens, Osteoporosis Med, Suddenly, Hot Therapy for Muscle Growth, and Much, Much More

Issue 165

Good afternoon Nikkola Newsletterers!

We just surpassed 5,000 subscribers! Thank you for supporting and sharing the Nikkola Newsletter with your friends and family.

I have to give a quick shout-out to Chris Long for using the referral program for the first time. Your first reward is on the way.

Being that we just surpassed this milestone, I thought it was time for a check-in to see how I can improve the Nikkola Newsletter to ensure it’s a valuable addition to your inbox and your life in general.

Your input is extremely valuable. After all, I publish this newsletter for you and people just like you.

Thanks again for being part of the Nikkola Newsletter family. I hope the newsletter continues to be a small but significant influence on your health and fitness.

Enjoy today’s carefully curated content.

Today is the final day to register at the discounted rate!!

Get Fit for the Feast!

The holiday season is notorious for derailing fitness goals. But what if this year could be different? Imagine stepping into the holiday season in your best shape all year, inspiring your family and friends to make healthier choices. With the Fit for the Feast 4-Week Challenge, you'll not only feel, look, and function better for the holidays, you'll also be able to enjoy them more!

Oh, and you also get the chance to win some cool stuff, too!

📖 Deep Dive

Anti-Androgens: Beware of Supplements That Suppress Testosterone. Like pharmaceuticals, nutritional supplements rarely cause only one effect on your physiology. Sometimes, supplements offer numerous health benefits and few, if any, side effects. On the other hand, some supplements provide benefits for certain people while also causing undesirable side effects. Such is the case with many anti-androgen supplements. You might have only read of the benefits of the supplements below. For example, you might think of saw palmetto and imagine a healthy prostate. But you don’t consider the fact that saw palmetto supports a healthy prostate, at least in part, by suppressing testosterone. In this blog post, I cover some of the most well-known and research-supported anti-androgen supplements. Keep reading (or listen to) article…


Professional Quality Meets Practical Convenience

Introducing my new, customized Daily Packs, available exclusively through my Fullscript account.

I created two unique daily supplement packs, a Women’s Fitness Daily Pack and a Men’s Fitness Daily Pack, with the goal of getting your basic nutrition needs met. Rather than having you order multiple bottles of supplements, I combined multiple products into one, delivered in morning and evening packets.

In the coming weeks, I’ll create some additional, goal-specific all-in-one packs as well. If this sounds like what you need, reply to this email.

As usual, you get 15% off one-time orders and 20% off when using autoship. Tap the button below to see what’s included in these new daily packs. You’ll see these custom packs after you log in.

I practice what I preach. I wouldn’t make a Men’s Fitness Daily Pack to promote to other men if I wouldn’t use it myself. I already ordered mine. It’ll be on my autoship going forward.

🩺 Health

Malaria drug could treat osteoporosis. Research from China's Peking University International Cancer Institute reveals that the malaria drug dihydroartemisinin (DHA) could be a game-changer in treating osteoporosis. Utilizing artificial intelligence, the researchers pinpointed how DHA impacts the differentiation of bone marrow mesenchymal stem cells into osteoblasts, the cells responsible for bone formation. In mouse models, oral DHA treatments led to reduced bone loss and improved bone structure. The study takes osteoporosis treatment a step further by focusing on reinforcing existing bone rather than merely slowing its breakdown. With its encouraging results and minimal toxicity, DHA could be a pivotal therapeutic agent in osteoporosis treatment, changing the game in how we address bone health. You probably know what my last word on this topic will be about: Treating bone density requires giving your body a reason to build denser bones. You need to strength train. Without it, even the most amazing treatments will have minimal effects.

Died suddenly: with vs. without vaccine: In a staggering revelation, the data on "died suddenly" deaths post-COVID vaccination is raising some tough questions. Research conducted by Mark Crispin Miller suggests that out of 10,000 cases of sudden deaths he tracked, only one was unvaccinated. Given that 25% of Americans remain unvaccinated, we'd statistically expect to see around 2,500 unvaccinated individuals in this sample. Instead, we find an almost negligible number—just 10. The probability of this discrepancy occurring by random chance is astronomically low, even if we were to adjust Miller's numbers by three orders of magnitude. Something isn't adding up, and the question looms: what is causing this marked discrepancy in sudden deaths between the vaccinated and unvaccinated?

Heat, not cold for muscle growth and maintenance. Cold plunges are all the rage right now, but there’s one issue people need to be aware of. Cold is counterproductive for muscle growth or maintenance. Heat, on the other hand, triggers muscle growth. Evidence shows it can have a small effect even without exercise, but definitely when combined with strength training. The perfect combination? Strength training + sauna (pronounced “sow-nah” not “saw-nah”).

🥩 Nutrition

Prebiotics curb appetite. New research from the University of Leipzig Medical Center suggests that prebiotics, found abundantly in foods like onions and garlic, could offer a less-invasive strategy for obesity management by influencing the brain's response to food. Published in the journal Gut, the study administered 30 grams of inulin, a prebiotic found in chicory root, to overweight adults and analyzed their brain activity via MRI scans. The results showed that the participants' brain reward centers exhibited reduced activity in response to calorie-rich foods after prebiotic consumption. This groundbreaking research points to a fascinating gut-brain connection that may play a critical role in the choices we make about our food.

More support for a high-protein diet. If you’ve been reading my content for a while, you’ve no doubt seen me repeatedly recommend a higher-protein diet. The research support is almost overwhelming at this point, as another research review points out. This screenshot from the article sums it up well:

💊 Supplements

Melatonin fights obesity and fatty liver disease. In a recent study, scientists have found new ways melatonin can help fight obesity and fatty liver disease. We already knew that melatonin can help keep weight and liver fat in check. But this study goes a step further. For the first time, it shows that melatonin can actually slow down the body's absorption of fats by targeting a specific protein called NPC1L1. The study also found that melatonin reduces levels of a bad type of cholesterol. While more research is needed, these discoveries suggest melatonin could be a game-changer in treating obesity and liver issues.

And curcumin also helps with fatty liver. New research shows that curcumin, a compound found in turmeric, can be a real game-changer for those dealing with fatty liver caused by a high-fat diet. The scientists found that curcumin helps to lower levels of bad cholesterol and fats in both the blood and liver. How does it do this? By targeting and reducing levels of a specific protein known as NPC1L1, which is crucial for cholesterol absorption. In simpler terms, curcumin blocks the body's "fat and cholesterol gateway," helping to keep the liver healthier. This makes curcumin a promising option for those looking to manage or prevent nonalcoholic simple fatty liver (NASFL).

If personal development is a priority for you, you’ve got to check this out!

🌎 Other News & Stories Worth Reading

Professor encourages activist to start 'mass movement' for kids' right to sex work. A Johns Hopkins University professor appeared to advise a self-described sex work activist to create a "mass movement" to promote the idea of children in the sex industry, according to audio recorded by an undercover journalist during the Socialism 2023 conference. Keep reading… 

World Leaders Incite Riots Against U.S., Israel by Spreading Hamas Lies on Hospital. World leaders, journalists, and activists helped fuel anti-American riots around the Middle East Tuesday evening by spreading the false claim by the Palestinian terror group Hamas that an Israeli airstrike killed 500 Palestinian civilians at a hospital in Gaza. Keep reading…

In faith, fitness, and fortitude,
Tom Nikkola, CSCS

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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